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. 2017 Jul 21;9(3):24. doi: 10.3390/pharmaceutics9030024

Figure 4.

Figure 4

Macroscopic appearance of colon histology: (a) negative control: healthy, vehicle, water; (b) positive control: TNBS-induced and given only vehicle; (c) TPGS-curcumin suspension 60 mg/kg BW; (d) TPGS-stabilized curcumin nanosuspension 1.8 mg/kg BW; (e) standard drug-mesalamine 180 mg/kg BW. As depicted, chronic inflammation has progressed intensively in the untreated group. This progression has attenuated after treatments, especially using the curcumin nanoparticle. Each group consisted of six rats.