Table 6.
Macroscopic Observation of the Colon, Adhesion Scoring, and Hematocrit Measurement of Treated Groups.
| Group (n = 6) | Colon Weight (g) | Colon Index (%) | Colon Length (cm) | Lesion Number | Adhesivity | Hematocrit |
|---|---|---|---|---|---|---|
| a | 1.33 ± 0.30 * | 0.67 ± 0.13 * | 13.42 ± 1.32 * | 1.33 ± 2.16 * | 2.33 ± 1.97 | 0.39 ± 0.02 * |
| b | 1.90 ± 0.08 | 0.91 ± 0.11 | 8.58 ± 1.49 | 20.33 ± 2.73 | 1.83 ± 0.41 | 0.27 ± 0.06 |
| c | 1.61 ± 0.12 * | 0.77 ± 0.03 * | 11.07 ± 1.99 * | 14.17 ± 1.72 * | 0.33 ± 0.52 | 0.38 ± 0.03 * |
| d | 1.36 ± 0.26 * | 0.69 ± 0.13 * | 11.47 ± 1.12 * | 12.17 ± 2.48 * | 0.33 ± 0.52 | 0.43 ± 0.03 * |
| e | 1.42 ± 0.06 * | 0.69 ± 0.11 * | 11.08 ± 0.47 * | 15.16 ± 3.43 * | 1.40 ± 0.55 | 0.37 ± 0.05 * |
Group a (negative control: healthy, vehicle, water); group b (positive control: TNBS-induced and given only vehicle); group c (TPGS-curcumin suspension 60 mg/kg BW); group d (TPGS-stabilized curcumin nanosuspension 1.8 mg/kg BW); group e (standard drug-mesalamine 180 mg/kg BW). * significantly different as compared to untreated group (b) (p < 0.05).