Table 1. Top 10 down- or upregulated DEGs between LADC and LSCC in lung cancer dataset, GSE28571.

Probe set ID	Gene symbol	Gene description	Gene feature	Fold change
209125_at	KRT6A	keratin 6A	downregulation	−176.148978
206165_s_at	CLCA2	chloride channel accessory 2	downregulation	−90.443266
235075_at	DSG3	desmoglein 3	downregulation	−88.129812
201820_at	KRT5	keratin 5	downregulation	−82.362516
217272_s_at	SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	downregulation	−64.457025
213680_at	KRT6B	keratin 6B	downregulation	−52.540652
204455_at	DST	dystonin	downregulation	−46.258579
209863_s_at	TP63	tumor protein p63	downregulation	−45.820729
206032_at	DSC3	desmocollin 3	downregulation	−43.549951
204855_at	SERPINB5	serpin peptidase inhibitor, clade B (ovalbumin), member 5	downregulation	−39.535047
244056_at	SFTA2	surfactant associated 2	upregulation	31.032507
228979_at	SFTA3	surfactant associated 3	upregulation	27.153369
211024_s_at	NKX2-1	NK2 homeobox 1	upregulation	15.422392
219580_s_at	TMC5	transmembrane channel-like 5	upregulation	11.725501
229105_at	GPR39	G protein-coupled receptor 39	upregulation	6.443132
214033_at	ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	upregulation	6.288185
212328_at	LIMCH1	LIM and calponin homology domains 1	upregulation	6.28786
225822_at	TMEM125	transmembrane protein 125	upregulation	5.919894
230875_s_at	ATP11A	ATPase, class VI, type 11A	upregulation	5.787312
228806_at	RORC	RAR-related orphan receptor C	upregulation	5.335111