Rhodopsin |
N/A |
Light sensitivity |
N/A |
31 |
FOXO3 |
ALL |
Pro-apoptotic signaling, LIC maintainence |
Pro/anti-tumorigenic |
73 |
CD38 |
N/A |
immune checkpoint signaling |
Poor prognostic marker in leukemias |
35 |
IKKβ |
CLL |
NF-kB activator |
pro-tumorigenic |
33 |
Caspase-2 |
Bladder |
DNA repair & pro-apototic signaling |
anti-tumorigenic |
94 |
CDKN2B |
CRC |
Cell cyle inhibitor |
anti-tumorigenic |
98 |
NNAT |
Breast, Prostate |
Increased Ca2+ to promote ERK/FAK signaling |
pro-tumorigenic |
53, 164 |
CD276 |
Breast |
Inhibits T-cell activation |
pro-tumorigenic |
111 |
LSD1 |
Breast |
Demethylase |
pro-tumorigenic |
117 |
EYA3 |
Ewing's Sarcoma |
DNA repair |
pro-tumorigenic |
131 |
Rap1b |
Ovarian |
promotes integrin-mediated focal adhesion |
pro-tumorigenic |
44 |
CD44 |
Prostate |
various oncogenic pathways |
pro-tumorigenic |
160 |
AKT2 |
Prostate |
PI3K signaling |
pro-tumorigenic |
160 |
KPNA4 |
Prostate |
shuttles transcription factors into nucleus |
pro-tumorigenic |
165 |
BMI1 |
RCC |
DNA repair |
pro-tumorigenic |
175 |
ZEB2 |
RCC |
promotes EMT |
pro-tumorigenic |
175 |
Survivin |
RCC, Lung |
inhibitor of apoptosis |
pro-tumorigenic |
175, 193 |
cFLIPL |
RCC |
Suppresses apoptotic signaling |
pro-tumorigenic |
176 |
p21 |
Lung |
Suppresses apoptotic signaling |
pro-tumorigenic |
193 |