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. Author manuscript; available in PMC: 2018 Nov 1.
Published in final edited form as: Apoptosis. 2017 Nov;22(11):1380–1393. doi: 10.1007/s10495-017-1409-8

Figure 8. Metformin protects HG-induced loss in cell viability in INS-1 832/13 cells.

Figure 8

INS-1 832/13 cells were incubated with low [2.5 mM] or high [20mM] glucose for 24 hrs. in the absence or presence of metformin [30 μM]. After 24 hrs. of glucose treatment, the cells were incubated with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide [MTT] reagent for 4 hrs. and absorbance was measured at 540 nm. Data are represented as mean ± SEM from 8–10 determinations in each condition. *p=0.033, ** p=0.0001; and *** p=0.78 [not significant] vs. basal conditions.