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. 2017 May 16;8(43):73905–73924. doi: 10.18632/oncotarget.17879

Table 1. Comparative cytotoxicities of the hydroxystilbenes against the human neuroblastoma cell linesa.

Compound % Viability loss – IMR32 cells % Viability loss – SHSY-5Y cells
25 μM 50 μM 50 μM 75 μM
1 44.5 ± 4.2* 60.0 ± 4.6** 41.3 ± 3.4* 55.9 ±3.9**
2 18.2 ± 2.6 23.7 ± 2.2* 13.2 ± 1.6 22.8 ± 1.9*
3 35.0 ± 2.3* 45.4 ± 4.1* 38.2 ± 4.1* 41.2 ± 3.6*
4 37.8 ± 3.9* 16.2 ± 2.8 27.7 ± 1.9* 40.9 ± 5.1*
5 23.7 ±1.6* 27.2 ± 2.8* 17.8 ± 1.4 23.0 ± 2.2*
Resv 27.2 ± 1.8* 42.8 ± 4.7* 30.0 ± 3.6* 47.6 ± 5.1**

aThe cells were incubated with vehicle alone or in the presence of the hydroxystilbenes under complete growth conditions. The cell viability at 48 h was assayed by the MTT method. The percentages of reduction in viable cells were calculated considering the percentage of viable cells of the vehicle-treated control as 100. All determinations were made in five replicates in 3-4 different experiments and the values are mean ± S.E.M. *p<0.05, **p<0.01 compared to vehicle control.