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. 2017 Jul 19;8(43):74276–74286. doi: 10.18632/oncotarget.19395

Figure 6. ZNRF3 overexpression rescued tumor proliferation-promoting effects by miR-146a.

Figure 6

(A) The effects of ZNRF3 overexpression on cell proliferation in miR-146a-transfected MG-63 and HOS cells indicated by MTT assay. (B) The effects of ZNRF3 overexpression on the protein expression of GSK-3β/β-catenin pathway in miR-146a-transfected OS cells indicated by western blotting. (C, D) Real-time PCR and western blot analysis of the expression levels of ZNRF3 in sh-ZNRF3 and sh-miR-146a co-transfected U-2 OS and Saos-2 cells. (E) MTT analysis of cell proliferative activities of U-2 OS and Saos-2 cells co-transfected by sh-ZNRF3 and sh-miR-146a. *P<0.05, **P<0.01.