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(A) WT mice and IKKε null (-/-) mice received B16-F10 melanoma cells by tail-vein injection. Two weeks later, melanoma metastasis was visually assessed (n=6/group). (B) Quantification of pleural melanoma colonies. (C) The isolated cells from bronchoalveolar lavage fluid (BALF) were analyzed by CD8 staining. (D) Mouse survival was shown by Kaplan–Meier survival curves. *P<0.05.
