Figure 1. The identification of SIRT6-overexpressed HCC cells and the effects of SIRT6 overexpression on HCC cell proliferation.
(A and B) SIRT6 expression was only detected in HepG2-SIRT6 cells and HCCLM3-SIRT6 cells by anti-Flag, which suggests that stable SIRT6-overexpressed cell lines were successfully established. (C and D) Overexpression of SIRT6 decreased the proliferation of HepG2 cells from 48 hours and HCCLM3 cells from 72 hours. *P<0.05.