Figure 1. P72 phenotype of p53 induces cell survival and endothelial cell tubular formation.

Increased cell survival in cells that express P72^wt phenotype or mutant phenotypes compared to cells that express R72^wt phenotype (A and B). Conditioned medium of P72^wt or mutant phenotypes expressing cells induce HUVEC to form networks of multiple tube-like structures, while conditioned medium of R72^wt expressing cells did not support tubule formation (C).