Table 3. The joint effect of the two SNPs.
| Stratum | Model* | Cases | HR | 95% CI | P value |
|---|---|---|---|---|---|
| Smokers | 0 | 39 | 1.00 | ||
| 1 | 71 | 1.29 | 0.83–2.00 | 0.252 | |
| 2 | 67 | 1.66 | 1.07–2.59 | 0.024 | |
| 3 + 4 | 25 | 3.00 | 1.75–5.13 | < 0.001 | |
| AD | 0 | 48 | 1.00 | ||
| 1 | 85 | 1.24 | 0.93–1.86 | 0.289 | |
| 2 | 68 | 1.30 | 0.85–1.98 | 0.226 | |
| 3 + 4 | 36 | 2.20 | 1.35–3.58 | 0.001 | |
| SQU | 0 | 26 | 1.00 | ||
| 1 | 58 | 0.84 | 0.51–1.40 | 0.505 | |
| 2 | 58 | 1.64 | 0.99–2.72 | 0.054 | |
| 3 + 4 | 22 | 1.85 | 1.01–3.39 | 0.047 | |
| III/IV | 0 | 47 | 1.00 | ||
| 1 | 108 | 1.22 | 0.85–1.75 | 0.290 | |
| 2 | 107 | 1.53 | 1.06–2.19 | 0.023 | |
| 3 + 4 | 41 | 2.00 | 1.30–3.09 | 0.002 | |
| Chemotherapy | 0 | 80 | 1.00 | ||
| 1 | 154 | 1.15 | 0.85–1.55 | 0.364 | |
| 2 | 138 | 1.41 | 1.04–1.91 | 0.029 | |
| 3 + 4 | 60 | 1.67 | 1.16–2.41 | 0.006 |
*0:AA of microRNA 30c-1 polymorphisms and TT of microRNA 27a polymorphisms, 1: AG of microRNA 30c-1 polymorphisms and TT of microRNA 27a polymorphisms, or AA of microRNA 30c-1 polymorphisms and CT of microRNA 27a polymorphisms, 2: GG of microRNA 30c-1 polymorphisms and TT of microRNA 27a polymorphisms, or AA of microRNA 30c-1 polymorphisms and CC of microRNA 27a polymorphisms, or AG of microRNA 30c-1 polymorphisms and CT of microRNA 27a polymorphisms, 3: AG of microRNA 30c-1 polymorphisms and CC of microRNA 27a polymorphisms, or GG of microRNA 30c-1 polymorphisms and CT of microRNA 27a polymorphisms, 4:AA of microRNA 30c-1 polymorphisms and CC of microRNA 27a polymorphisms.