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. Author manuscript; available in PMC: 2017 Dec 26.
Published in final edited form as: Oncogene. 2017 Jun 26;36(43):5939–5947. doi: 10.1038/onc.2017.197

Figure 5. Interactions between JNK and PARP-1, and effects of JNK deletion on PARP-1 protein expression and serine phosphorylation.

Figure 5

(A) Immunoprecipitation with PARP-1 antibody and immunoblotting with antibodies against PARP-1, phosphorylated serine (P-Ser) or JNK1/2 were performed using cell lysates prepared from MKP-1+/+ and MKP-1−/− MEFs treated with 2 μg/mL cisplatin for 24 hr. (B) Immunoprecipitation with PARP-1 antibody and immunoblotting with antibodies against PARP-1, phosphorylated serine, or JNK1/2 were performed using cell lysates prepared from JNK1/2+/+ and JNK1/2−/− MEFs.