Skip to main content
. 2017 Aug 3;8(47):81860–81872. doi: 10.18632/oncotarget.19899

Figure 7. Inhibition of bsAb on the production of IL-6 and IL- 8 and proliferation, and migration of FLS.

Figure 7

FLS cells were stimulated with TNF-α and IL-17A or in the presence of different, antibodies. A. The mRNA levels of IL-6 and IL- 8 were determined by realtime-PCR. B. Secretions of cytokines (IL-6 and IL-8) in culture media were measured by ELISA. C. Anti-proliferative effects of bsAb on FLS. After FLS cells were incubated with TNF-α and IL-17A, antibodies was added during the incubation. Cell proliferation was assessed using MTT assay. D. The anti-migration effects of bsAb on FLS were evaluated by the scratch assay. After wounds were formed, FLS were incubated with antibodies in the presence of TNF-α and IL-17A. Parallel lines represent the borders of the wounds.