Table 1.
Summary of the studies reporting NEN incidence and the SEER Program of the National Cancer Institute
| First author, publication year | Study period | Country | Study area | Total cases | Incidence rates, type of adjustment | Subsites of NEN incidence |
|---|---|---|---|---|---|---|
| North America | ||||||
| SEER [present series] | 1973–2012 | USA | 1973–1991: 9 Registries, 1992–1999: 13 Registries, 2000–2012: 18 Registries | na | Age-standardized, 2000 US Standard Population | Overall, lung, stomach, pancreas, small intestine, colon, appendix, rectum |
| Hallet, 2015 | 1994–2009 | Canada | Ontario | 5619 | Crude | Overall, lung, stomach, pancreas, small intestine, colon, appendix, rectum |
| Europe | ||||||
| Korse, 2013 | 1990–2010 | Netherlands | Nationwide | 47,800 | Age-standardized, European Standard Population | Overall, lung, stomach, pancreas, small intestine, appendix, rectum |
| Scherubl, 2013 | 1976–2006 | Germany | Mecklenburg-Western Pomerania, Saxony, Brandenburg or Thuringi | 2821 | Age-standardized, Population of Germany in 1987 | Stomach, pancreas, small intestine, colon, appendix, rectum |
| Caldarella, 2011 | 1985–2005 | Italy | Firenze and Prato | 455 | Age-standardized, 2000 European Standard Population | Overall |
| Ellis, 2011 | 1971–2006 | England | Nationwide | 10,324 | Crude | Stomach, small intestine, colon, appendix, rectum |
| Landerholm, 2010 | 1960–2005 | Sweden | Jonkoping County | 145 | Age-standardized, Population of Sweden in 2005 | Small intestine |
| Hauso, 2008 | 1993–2004 | Norway | Nationwide | 2030 | Age-standardized, 2000 US Standard Population | Overall, lung, stomach, pancreas, small intestine, colon, appendix, rectum |
| Lepage, 2006 | 1976–2001 | France | Burgundy | 102 | Age-standardized, World standard population | Small intestine |
| Skuladottir, 2002 | 1978–1997 | Denmark | Nationwide | 347 | Age-standardized, Population of Denmark in 1980 | Lung |
| Levi, 2000 | 1974–1997 | Switzerland | Vaud | 218 | Age-standardized, World Standard Population | Overall, lung, stomach, small intestine |
| Asia | ||||||
| Tsai, 2013 | 1996–2008 | Taiwan | Nationwide | 2187 | Age-standardized, 2000 US Standard Population | Overall, lung, stomach, small intestine, pancreas, rectum |
NEN neuroendocrine neoplasm, ICD-O International Classification of Disease for Oncology, SEER Surveillance, Epidemiology, and End Results