Correction
After publication of the original article [1] the authors noted that the following errors had occurred:
The name of the author H. Simon Schaaf had been incorrectly tagged as Simon H. Schaaf. This has been corrected in the author list above.
The first p value below Table 1 is listed as p < 0.011, however it should be p < 0.01. An updated version of this table is included with this Correction.
Table 1.
Baseline characteristics in children with household multidrug-resistant tuberculosis and drug-susceptible tuberculosis exposure
| Risk factors and clinical states | DS-TB exposure (n = 316) N (%) | MDR-TB exposure (n = 229) N (%) |
|---|---|---|
| Child factors | ||
| < 1 year | 48 (15.2) | 50 (21.8) |
| 1 year | 66 (20.9) | 41 (17.9) |
| 2 years | 71 (22.5) | 44 (19.2) |
| 3 years | 73 (23.1) | 56 (24.5) |
| 4 years | 58 (18.4) | 38 (16.6) |
| Male | 162 (51.3) | 119 (52.2) |
| Black African (vs. mixed race) | 52 (16.5) | 101 (44.1)** |
| HIV-positive | 1 (0.3) | 8 (3.7)* |
| BCG scar/vaccination documented | 310 (98.1) | 181 (81.2)** |
| Previous tuberculosis treatment | 8 (2.5) | 21 (9.2)* |
| Weight for age (z-score) < −2 | 32 (10.1) | 23 (10.1) |
| Sleeps in same room as TB source case | 79 (25.3) | 34 (15.0)** |
| Sleeps in same bed as TB source case | 20 (6.4) | 57 (25.2)** |
| Adult source case /household factors | ||
| Source case sputum acid-fast bacilli smear-positive | 181 (62.9) | 180 (80.0)** |
| Household tobacco smoke exposure | 245 (80.4) | 145 (63.3)** |
| Mean socioeconomic index (x/11), n (standard deviation) | 4.0 (2.6) | 4.1 (2.5) |
| Clinical states | ||
| Exposure no infection | 205 (65.7) | 125 (61.3) |
| Infection no disease | 80 (25.6) | 86 (38.1)* |
| Disease | 27 (8.7) | 15 (6.6) |
MDR-TB Mycobacterium tuberculosis resistant to rifampicin and isoniazid (defined by line probe assay)
DS-TB Mycobacterium tuberculosis susceptible to rifampicin and isoniazid (defined by line probe assay)
p < 0.01*; p < 0.001**
The original article has also been corrected.
Footnotes
Vera Golla and Kathryn Snow are Joint first authors.
Anneke C. Hesseling and James A. Seddon are Joint last authors.
The original article can be found online at https://doi.org/10.1186/s12879-017-2668-2.
Contributor Information
Anneke C. Hesseling, Email: annekeh@sun.ac.za
James A. Seddon, Email: james.seddon@imperial.ac.uk
Reference
- 1.Golla V, Snow K, Mandalakas AM, Schaaf HS, Du Preez K, Hesseling AC, Seddon JA. The impact of drug resistance on the risk of tuberculosis infection and disease in child household contacts: a cross sectional study. BMC Infect Dis. 2017;17:593. doi:10.1186/s12879-017-2668-2. [DOI] [PMC free article] [PubMed]