Table 1. Clinicopathological correlation analysis of miR-526b expression in hepatocellular carcinoma.
Clinicopathologic features | miR-526b expression | P | ||
---|---|---|---|---|
High level (n=40) | Low level (n=40) | |||
Age (y) | ≤50 | 15 | 17 | 0.648 |
>50 | 25 | 23 | ||
Sex | Male | 33 | 35 | 0.531 |
Female | 7 | 5 | ||
HBsAg | No | 4 | 7 | 0.330 |
Yes | 36 | 33 | ||
Serum AFP level (ng/mL) | ≤20 | 14 | 10 | 0.329 |
>20 | 26 | 30 | ||
Tumor size (cm) | ≤5 | 15 | 6 | 0.022* |
>5 | 25 | 34 | ||
No. of tumor nodules | 1 | 36 | 32 | 0.210 |
≥2 | 4 | 8 | ||
Cirrhosis | Absent | 13 | 7 | 0.121 |
Present | 27 | 33 | ||
Venous infiltration | Absent | 25 | 14 | 0.014* |
Present | 15 | 26 | ||
Edmondson-Steiner grading | I+II | 34 | 27 | 0.066 |
III+IV | 6 | 13 | ||
TNM tumor stage | I+II | 36 | 29 | 0.045* |
III+IV | 4 | 11 |
HBV, hepatitis B virus; AFP, alpha-fetoprotein; TNM, tumor-node-metastasis. *Statistically significant.