Table 7. The characteristics of five SNPs found in miRNAs and their related association studies with cancers.
| miRNA locus | Function | SNPs | Alleles (case/control) | Diseases/reference | Population(region) | P value | |
|---|---|---|---|---|---|---|---|
| Pri-miR-218-2 | Anti-oncogene | rs11134527 | A | G | |||
| 1321/1538 | 897/1012 | ESCC [26] | Han Chinese (Taizhou and Shanghai) | 0.595 | |||
| 346/599 | 258/427 | HCC [27] | Han Chinese (Sichuan) | 0.670 | |||
| 1928/1662 | 1202/1120 | Cervical Cancer [28] | Han Chinese (Shanghai) | 0.145 | |||
| Pri-miR-124-1 | Anti-oncogene | rs531564 | C | G | |||
| 1901/2151 | 317/399 | ESCC [26] | Han Chinese (Taizhou and Shanghai) | 0.191 | |||
| 290/434 | 26/86 | Cervical Cancer [37] | Han Chinese (Zhengzhou) | 0.001 | |||
| 197/353 | 17/63 | Cervical Cancer [38] | Han Chinese (Guangdong) | 0.014 | |||
| Pri-miR-145 | Anti-oncogene | rs74693964 | C | T | |||
| no reference | no reference | no reference | no reference | no reference | |||
| Pri-miR-133a2 | Anti-oncogene | rs6062251 | C | T | |||
| no reference | no reference | no reference | no reference | no reference | |||
| Pri-miR-100 | Anti-oncogene | rs1834306 | A | G | |||
| 217/189 | 279/399 | ESCC [50] | Kazakh Chinese (Xinjiang) | 8.37×10−5 | |||
| 92/377 | 114/457 | Cervical Cancer [51] | Han Chinese (Guangzhou) | 0.892 |