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. Author manuscript; available in PMC: 2017 Nov 14.
Published in final edited form as: Alcohol. 2016 Jun 11;58:25–32. doi: 10.1016/j.alcohol.2016.05.005

Fig. 4.

Fig. 4

Two cycles of ethanol exposure and withdrawal decreased dopamine synthesis in the ventral striatum. (A) Baseline dopamine synthesis is unchanged by two cycles of ethanol exposure and withdrawal in the midbrain of C57 mice. (B) Dopamine synthesis is reduced by two cycles of ethanol exposure and withdrawal in the ventral striatum, and unchanged in the dorsal striatum (C). (D) Quinpirole-induced inhibition of dopamine synthesis is decreased in the midbrain of ethanol-exposed mice as compared to air-exposed controls. In contrast, quinpirole-induced decreases in dopamine synthesis are unaffected by two cycles of ethanol exposure and withdrawal in the ventral (E) and dorsal (F) striatum. *p < 0.05.