Table 1. Characteristics of the studies included in the meta-analysis.
| Year | Author | Age (mean) C/CTL | Gender (male %) C/CTL | Sample size C/CTL | Duration before admission | Treatment modality | Measuring methods | TIMI grade (number) |
|---|---|---|---|---|---|---|---|---|
| 2016 | Teunissen [22] | 59/59 | 78/78 | 30/30 | ≦ 6 h | PCI & antiplatelet & anticoagulation | ELISA | 3 (57)2 (3) |
| 2015 | Regueiro [32] | 53.7/54.7 | 85/84.7 | 100/98 | ≦ 24 h | PCI or Thrombolysis | ELISA | NR |
| 2012 | Jia [23] | 62.64/ 47.45 | 73/68 | 48/19 | NR | Antiplatelet & anticoagulation | ELISA | NR |
| 2011(1) | Zhou [24] | 63.4/58.44 | 58/60 | 43/22 | NR | PCI | ELISA | 3 (43) |
| 2011(2) | Zhou [24] | 63.4/58.44 | 60/60 | 43/21 | NR | PCI | ELISA | ≦ 2 (43) |
| 2007 | Matsukawa [25] | 65/65 | 73/63 | 92/40 | ≦ 24 h | PCI & antiplatelet | ELISA | NR |
| 2000 | Sakai [27] | 59/50 | NR | 51/58 | ≦ 6 h | PCI & antiplatelet & anticoagulation | EIA | NR |
| 2000 | Lip [31] | 62/62 | 70/70 | 17/59 | ≦ 12 h | Thrombolysis & anticoagulation | ELISA | NR |
| 2000 | Xie [26] | 68/61 | 75/50 | 16/16 | NR | PCI or Thrombolysis | EIA | 3 (16) |
| 1996 | Tousoulis [28] | 60/46 | 94/38 | 16/8 | NR | Antiplatelet & anticoagulation | ELISA | NR |
| 1992 | Norris [29] | 58/52 | 81/81 | 51/36 | ≦ 6 h | Thrombolysis | EIA | NR |
| 1990 | Andreotti [30] | 58/58 | 71/71 | 12/12 | ≦ 6 h | Thrombolysis & anticoagulation | ELISA | ≧ 2 (16)< 2 (8) |
Abbreviations: C/CTL, case/control group; NR, unreported; PCI, percutaneous coronary intervention; ELISA, enzyme-linked immunosorbent assay; EIA, enzyme immunoassay; TIMI, thrombolysis in myocardial infarction.