In the article titled “The Controversial C5a Receptor C5aR2: Its Role in Health and Disease” [1], there was an error in Table 4, where Jun/fos-A8△71–73 should be corrected to A8△71–73. The corrected table is as follows:
Table 4.
Ligand | Specificity | Function | Refs |
---|---|---|---|
Jun/fos-A8 A8△71–73 C5 mutant peptides |
Human and murine C5aR1 and C5aR2 | Antagonists—block binding of C5a and C5a des Arg to C5aRs |
[51] |
P32, P59—C terminal peptides of C5a | hC5aR2 | Agonists—strongly stimulate the association of hC5aR2 with β-arrestin 2 | [21, 127] |
LukS-PV—protein from S. aureus | Human and rabbit C5aR1 Human, macaque, and rabbit C5aR2 |
Antagonist of C5a-induced activation of neutrophils | [48, 128] |
HIgCB—protein complex from S. aureus | Human, macaque, rabbit, and cow C5aRs | Antagonist of C5a-induced activation of neutrophils | [128, 129] |
References
- 1.Zhang T., Garstka M. A., Li K. The controversial C5a receptor C5aR2: its role in health and disease. Journal of Immunology Research. 2017;2017:16. doi: 10.1155/2017/8193932.8193932 [DOI] [PMC free article] [PubMed] [Google Scholar]