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. 2017 Oct 4;8(51):88870–88881. doi: 10.18632/oncotarget.21488

Figure 1. The expression and prognostic value of miR-216a in GC.

Figure 1

(A) The relative expressions of miR-216a in 90 pairs of GC tissues and matched noncancerous tissues. Data were presented as log2 of fold change of GC relative to matched noncancerous tissues and analyzed by student’s t-test. (B) qRT-PCR analysis of miR-216a expression in GC cell lines (SGC-7901, MGC-803, MKN-28, and BGC-823) and the normal human gastric epithelium cell line (GES-1). n = three repeats with similar results, *P<0.05 by ANOVA. (C) GC patients were divided into miR-216a high expression group and miR-216a low expression group based on the median level of miR-216a expression. GC patients with low miR-216a level (n = 45) had an obvious shorter overall survival compared to those with high miR-216a level (n = 45). P<0.05 by Log-rank test.