Table 3. Stratification analysis of MDM4 genotypes, OR, and 95% CIs by selected variables.
| Variable | HPV16+ patients (N =439) | HPV16- patients (N =113) | Adjusted OR (95%CI)* | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No risk | With 1-3 risk | No risk | With 1-3 risk | No variants† | With variants | |||||
| No. | % | No. | % | No. | % | No. | % | |||
| All subjects | 85 | 19.4 | 354 | 80.6 | 43 | 38.1 | 70 | 61.9 | 1.0 | 2.5 (1.6-3.9) |
| Age | ||||||||||
| ≤54 years | 50 | 22.2 | 175 | 77.8 | 18 | 30.5 | 41 | 69.5 | 1.0 | 1.6 (1.0-3.0) |
| >54 years | 35 | 16.4 | 179 | 83.6 | 25 | 46.3 | 29 | 53.7 | 1.0 | 1.9 (0.9-2.7) |
| Sex | ||||||||||
| Male | 75 | 19.5 | 309 | 80.5 | 32 | 37.6 | 53 | 62.4 | 1.0 | 2.8 (1.4-3.9) |
| Female | 10 | 18.2 | 45 | 81.8 | 11 | 39.3 | 17 | 60.7 | 1.0 | 3.1(1.1-9.2) |
| Ethnicity | ||||||||||
| Non-Hispanic White | 79 | 19.6 | 325 | 80.5 | 37 | 37.4 | 62 | 62.6 | 1.0 | 2.3 (1.4-3.8) |
| Others | 6 | 17.1 | 29 | 82.9 | 6 | 42.9 | 8 | 57.1 | 1.0 | 4.6 (0.9-21.7) |
| Smoking status | ||||||||||
| Ever | 51 | 20.2 | 201 | 79.8 | 29 | 38.7 | 46 | 61.3 | 1.0 | 1.6 (0.7-3.5) |
| Never | 34 | 18.2 | 153 | 81.8 | 13 | 35.1 | 24 | 64.9 | 1.0 | 2.3 (1.1-5.0) |
| Drinking status | ||||||||||
| Ever | 66 | 19.9 | 265 | 80.1 | 30 | 34.1 | 58 | 65.9 | 1.0 | 2.0 (0.9-4.0) |
| Never | 19 | 17.6 | 89 | 82.4 | 12 | 50.0 | 12 | 50.0 | 1.0 | 4.6 (1.8-12.2) |
*Adjusted for age, sex, ethnicity, tobacco smoking and alcohol drinking status in a logistic regression model.
†Reference group.