Table 6. Single loci associations with high altitude polycythemia risk in Tibetan subjects.
SNP_ID | Model | Ref Allele | Alt Allele | OR | 95% CI | p value |
---|---|---|---|---|---|---|
rs934607 | Dominant | A | G | 0.340 | 0.136-0.847 | 0.021 |
Recessive | 0.191 | 0.033-1.107 | 0.065 | |||
Additive | 0.364 | 0.172-0.770 | 0.008 | |||
rs141267844 | Dominant | A | T | 0.361 | 0.148-0.878 | 0.025 |
Recessive | 0.290 | 0.061-1.390 | 0.122 | |||
Additive | 0.425 | 0.212-0.853 | 0.016 | |||
rs6710946 | Dominant | T | C | 6.005 | 1.661-21.710 | 0.006 |
Recessive | 4.283 | 2.374-17.374 | 0.999 | |||
Additive | 5.752 | 1.621-20.410 | 0.007 |
OR: odds ratio; 95% CI: 95% confidence interval; p<0.05 indicates statistical significance for genetic model.