Figure 1.

Expression pattern and localization of Survivin (SVV) in heart development and after myocardial infarction (MI). A, RT-PCR of SVV mRNA expression level during heart development. B, Western blot of SVV protein expression level in different development stages. C, Immunofluorescence staining of SVV expression in cardiomyocytes during heart development. cTnI, cardiac troponin I; blue, nucleus; green, cardiomyocyte marker. White bar, 20 μm; yellow bar, 5 μm. D, Quantification of SVV positive cardiomyocytes during different heart development stages. E, Western blot showing SVV protein expression levels at different time points after MI. F, Immunofluorescence staining showing localization of SVV after injury. White bar, 20 μm; yellow bar, 5 μm.