Table 1. Clinicopathological patient characteristics.
Variable | Value [mean ± SD (range)] | |
---|---|---|
Age (yrs) | 64 ± 15 (26 - 93) | |
Variable | Value [median (95% CI)] | |
Follow-up time (ms) | 46.7 (31.1 - 55.8) | |
Variable | Value [n (%)] | |
Tumor stage | pT1a | 16 (16) |
pT1b | 67 (65) | |
pT2 | 15 (14) | |
pT3 | 1 (1) | |
ND | 4 (4) | |
Depth of stromal invasion | ≤ 1mm | 12 (12) |
> 1mm | 75 (73) | |
ND | 16 (15) | |
Lymph node involvement | Present | 31 (30) |
Absent | 40 (39) | |
ND | 32 (31) | |
Metastasis | Present | 5 (5) |
Absent | 94 (91) | |
ND | 4 (4) | |
Tumor grade | 1 | 12 (12) |
2 | 66 (64) | |
3 | 24 (23) | |
ND | 1 (1) | |
Lymphovascular space invasion | Present | 8 (8) |
Absent | 80 (78) | |
ND | 15 (14) | |
Haemangioinvasion | Present | 6 (6) |
Absent | 82 (80) | |
ND | 15 (14) | |
Local surgical treatment | Wide local excision | 15 (15) |
Partial vulvectomy | 35 (34) | |
Vulvectomy | 49 (47)* | |
Punch biopsy only | 4 (4)** | |
Tumor-free margins | Present | 86 (84) |
Absent | 17 (16) | |
Lymph node dissection | Sentinel | 4 (4) |
Inguinal (uni-, bilateral) | 66 (64)*** | |
No lymph node dissection | 33 (32) | |
Radiation therapy | Vulvar | 12 (12) |
Inguinal | 8 (8) | |
Vulvar & inguinal | 22 (21)**** | |
No radiation | 61 (59) | |
Chemotherapy | Chemotherapy | 1 (1) |
Concurrent chemoradiation | 3 (3) | |
No chemotherapy | 99 (96) | |
Disease status | No evidence of disease | 64 (62) |
Recurrent disease | 36 (35) | |
Lost to follow-up | 3 (3) | |
Outcome | Alive | 61 (59) |
Tumor-related death | 33 (32) | |
Non tumor-related death | 8 (8) | |
Lost to follow-up | 1 (1) |
CI, confidence interval; ms, months; ND, not determined; SD, standard deviation; yrs, years.
*, includes 9 cases of concurent pelvic exenteration.
**, surgery was not performed due to death before surgery (2) or inoperable morbidity (2).
***, in 4 cases concurrent pelvic/paraaortic lymphadenectomy was performed.
****, in 12 cases concurrent pelvic/iliac radiation therapy was performed.