Table 2.
Hepatic and peripheral tissue IS of glucose metabolism in obese youth with IGT vs. NGT
| NGT (n = 97) | IGT (n = 41) | P | |
|---|---|---|---|
| Fasting HGP (mg/kg/min) | 2.3 ± 0.1 | 2.4 ± 0.1 | NS |
| Hepatic IS (mg/kg/min ⋅ µU/mL)−1 | 16.0 ± 0.8 | 11.8 ± 1.0 | 0.001 |
| Insulin-stimulated glucose disposal (mg/kg/min) | 6.1 ± 0.2 | 4.7 ± 0.3 | <0.0001 |
| Insulin-stimulated glucose oxidation (mg/kg/min) | 2.7 ± 0.1 | 2.3 ± 0.1 | 0.006 |
| Insulin-stimulated nonoxidative glucose disposal (mg/kg/min) | 3.3 ± 0.2 | 2.6 ± 0.3 | 0.028 |
| Peripheral IS (mg/kg/min per µU/mL) | 2.5 ± 0.2 | 1.7 ± 0.2 | 0.001 |
Values are reported as the mean ± SEM.