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. 2017 Oct 17;7(19):4699–4709. doi: 10.7150/thno.20654

Table 1.

Sera positive for anti-drug antibodies of patients treated with A) IFX or B) ADL. Patient sera were analyzed by a certified ELISA system for anti-drug antibodies (not resolving the isotype).

A) Infliximab-treated patients
ID anti-IFX [µg/mL] IFX serum c [µg/mL] ICRIP result
IFX438 54.1 < 4.0 ADL/IFX/IFX PI/bov TG
IFX452 63.9 4.9 bov TG
IFX485 74.1 18.3 neg.
IFX522 45.9 5.6 neg.
IFX638 39.3 < 4.0 neg.
IFX648 34.2 11.6 neg.
IFX652 29.7 < 4.0 neg.
IFX660 14.4 9.9 bov TG
IFX694 45.6 18.9 ADL PI/bov TG
IFX719 69.7 6.7 neg.
IFX721 > 80 11.4 neg.
IFX722 44.8 4.7 neg.
IFX724 32.6 < 4.0 neg.
IFX729 27.3 < 4.0 neg.
IFX752 18.8 < 4.0 neg.
IFX754 22.0 < 4.0 IFX/IFX PI
IFX767 67.5 26.1 neg.
IFX790 34.6 8.3 bov TG
IFX809 31.0 4.6 neg.
IFX883 46.1 < 4.0 neg.
IFX890 > 80 16.9 hu TG
IFX905 22.6 < 4.0 neg.
IFX922 > 80 21.3 IFX/bov TG
IFX928 59.9 7.6 neg.
IFX957 > 80 12.3 neg.
IFX963 73.9 28.0 neg.
IFX977 > 80 9.9 neg.
IFX982 29.4 < 4.0 neg.
IFX990 > 80 16.6 neg.
IFX996 > 80 20.5 neg.
B) Adalimumab-treated patients
ID anti-ADL [µg/mL] ADL serum c [µg/mL] ICRIP result
ADL41 2.4 13.6 n.t.
ADL67 12.1 > 256 n.t.
ADL72 18.5 > 256 n.t.
ADL86 5.7 > 256 CTX/HSA-α-Gal/bov TG
ADL89 22.4 > 256 n.t.
ADL90 2.3 < 4.0 n.t.
ADL122 8.7 4.2 n.t.
ADL123 14.2 > 256 n.t.
ADL134 34.9 28.3 n.t.
ADL138 < 1.25 n.a. neg.
ADL145 < 1.25 n.a. neg.
ADL149 7.6 7.7 CTX
ADL176 18.1 > 256 ADL/ADL PI
ADL178 > 40 12.7 CTX/bov TG/hu TG
ADL197 11.8 < 4.0 ADL/bov TG
ADL198 12.7 < 4.0 ADL/bov TG
ADL216 1.8 < 4.0 neg.
ADL242 3.4 < 4.0 n.t.
ADL245 2.9 < 4.0 neg.

ICRIP results are shown according to results in Fig. 2. For abbreviations of ICRIP analytes see Fig. 1. neg.: negative; n.a.: not available; n.t.: not tested (due to lack of sera).