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. 2017 Oct 6;8(55):94117–94128. doi: 10.18632/oncotarget.21587

Table 3. Prognostic factors on survival outcomes of 594 NPC patients by use of univariate analysis.

Characteristics LRRFS (%) P DMFS (%) P PFS (%) P OS (%) P
Sex 0.832 0.088 0.263 0.050
 Male 89.3 89.1 84.0 91.7
 Female 89.1 94.6 87.5 96.7
Age 0.164 0.824 0.737 0.061
 <60 89.7 91.0 85.0 94.2
 ≥60 86.9 90.2 85.8 88.5
T stage 0.851 0.937 0.686 0.948
 T1-T2 89.6 91.1 84.0 93.0
 T3-T4 89.2 90.9 85.4 93.8
N stage 0.192 0.001 0.012 0.008
 N0-N1 92.0 97.3 91.0 97.7
 N2-N3 88.4 88.0 82.5 91.3
Clinical stage 0.111 0.004 0.016 0.008
 III 90.5 93.5 87.3 95.6
 IVA/B 87.2 86.4 81.4 89.4
AC 0.225 0.735 0.707 0.330
 Yes 88.0 90.4 84.6 96.2
 No 91.6 91.6 86.1 92.7
NAC regimen 0.450 0.850 0.662 0.945
 TPF 88.2 91.6 83.9 93.6
 TP 91.7 91.2 87.5 92.5
 GP 93.8 91.8 89.8 95.9
 FP 86.2 88.5 82.6 92.7
NAC cycle 0.149 0.043 0.037 0.266
 2 cycles 91.3 93.3 88.7 94.0
 3 to 4 cycles 87.2 88.5 81.7 92.6

LRRFS, locoregional relapse-free survival; DMFS, distant metastases-free survival; PFS, progression-free survival; OS, overall survival; AC, adjuvant chemotherapy; NAC, neoadjuvant chemotherapy; TP, docetaxel/cisplatin; TPF, docetaxel/cisplatin/fluorouracil; GP, gemcitabine/cisplatin; FP, cisplatin/fluorouracil.