Table 3. Univariate and multivariate analysis of progression-free survival and overall survival in in 51 esophageal squamous cell carcinoma patients with celiac lymph node metastasis.
| Characteristics | No. of patients | Univariate analysis | Multivariate analysis | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|---|---|---|
| Median PFS (months) | P value | HR (95% CI) | P value | Median OS (months) | P value | HR (95% CI) | P value | ||
| Age | |||||||||
| < 60 years | 36 (71%) | 6.1 | 0.99 | 12.0 | 0.68 | ||||
| ≥ 60 years | 15 (29%) | 7.3 | 13.6 | ||||||
| Sex | |||||||||
| Male | 48 (94%) | 6.1 | 0.07 | 13.5 | 0.27 | ||||
| Female | 3 (6%) | 7.3 | 9.2 | ||||||
| T status | |||||||||
| 1 + 2 + 3 | 25 (49%) | 8.9 | 0.036* | 15.1 | 0.16 | ||||
| 4 | 26 (51%) | 3.8 | 10.5 | ||||||
| N status | |||||||||
| 0 + 1 + 2 | 19 (37%) | 11.2 | 0.009* | 0.44 (0.23-0.84) | 0.013* | 13.6 | 0.12 | ||
| 3 | 32 (63%) | 4.2 | 10.5 | ||||||
| Tumor stage | |||||||||
| IIIA + IIIB | 11 (22%) | 12.6 | 0.027* | 20.3 | 0.41 | ||||
| IIIC | 40 (78%) | 4.3 | 12.0 | ||||||
| Grade | |||||||||
| 1 + 2 | 29 (57%) | 6.1 | 0.19 | 19.1 | 0.030* | 0.34 (0.16-0.71) | 0.004* | ||
| 3 | 22 (43%) | 6.4 | 10.0 | ||||||
| Location | |||||||||
| Upper + Middle | 24 (47%) | 4.3 | 0.045* | 9.2 | 0.023* | ||||
| Lower | 27 (53%) | 8.9 | 15.1 | 0.41 (0.20-0.84) | 0.015* | ||||
PFS: progression-free survival; OS: overall survival; HR: hazard ratio; CI: confidence interval *Statistically significant.