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. 2017 Oct 3;8(53):90638–90650. doi: 10.18632/oncotarget.21469

Figure 7. HSF1 and c-Myc mRNA levels positively correlate in human HCC specimens.

Figure 7

A. Relationship between HSF1 and c-Myc expression levels; data were extracted from previous publications of our group and subjected to linear regression analysis [12, 15]. B., C. A statistically significant, positive correlation was also found between mRNA levels of HSF1 and those of two canonical c-Myc targets, namely ODC and LDHA. D. Example of c-Myc amplification patterns in HCC specimens as detected by fluorescence in situ hybridization (FISH). Upper panel: disomy (normal pattern); lower panel: c-Myc amplification.