Figure 6.

IFN-β supports MAP clearance. C57BL/6 (n = 3–10/group) were infected with PBS, MAP, MAP + 100 µg poly(I:C)/mouse, or MAP + 1000 units rIFN-β. Mice were killed at 14 dpi. (A) Schematic representation of the experiment. (B) spleen weight was determined. (C) Numbers of CFU in liver, (D) spleen and (E) mesentery were determined by plating. Data are representative of 2 independent experiments, *p<0.05, **p<0.01, ***p<0.001, ns (non-significant), by one-way ANOVA with Tukey post test, means ± SEM.