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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: ChemistrySelect. 2017 Mar 6;2(7):2335–2340. doi: 10.1002/slct.201700359

Scheme 1. Systematic truncation of aptamer KH1C12 and modification with 2’-O-methyl RNA bases.

Scheme 1

Affinity was determined 4°C with each construct calculated using the method described in ref[14]. Corresponding binding curves are listed in Figure S1. Red letters indicate 2’-O-methyl bases.