Table 3. mRNAs correlated with lncRNA-SVUGP2 level and dys-regulated in HCC.
| GeneSymbol | Regulation | Fold change | p value |
|---|---|---|---|
| CLEC4G | down | 39.53185 | 0.002215297 |
| MT1G | down | 340.1278 | 0.006273059 |
| FANCD2 | up | 7.532945 | 0.007258298 |
| HIST2H3A | up | 21.28292 | 0.000807 |
| MOGAT2 | down | 23.25504 | 0.008000504 |
| LCTL | up | 7.262519 | 0.003426997 |
| CHEK1 | up | 7.99765 | 0.0000196 |
| UGP2 | down | 6.343705 | 0.009276051 |
| KIAA0101 | up | 18.94839 | 0.003486132 |
| KIF23 | up | 24.93162 | 0.009041968 |
| TTK | up | 19.50945 | 0.008603159 |
| CENPM | up | 18.62225 | 0.007035683 |
| HOGA1 | down | 5.456985 | 0.007846125 |
The results of mRNA and lncRNA microarray done in 3 pairs of HCC and their adjacent noncancerous tissue were analyzed by Spearman's correlation test. mRNAs closely correlated with lncRNA-SVUGP2 were first selected (p < 0.05). Among these candidate mRNAs, 13 mRNAs were dramatically (Fold change > 5) and significantly (P-value < 0.01) dysregulated in HCC.