Table 5.
20–23 weeks (Exposure month=P5) |
24–27 weeks (Exposure month=P6) |
28–31 weeks (Exposure month=P7) |
32–36 weeks (Exposure month=P8) |
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---|---|---|---|---|---|---|---|---|
Case/Control | OR (95%CI)a | Case/Control | OR (95%CI)a | Case/Control | OR (95%CI)a | Case/Control | OR (95%CI)a | |
No. of chemical groups with any exposureb | ||||||||
0 | 393/142670 | Reference | 1384/142691 | Reference | 2343/142786 | Reference | 16871/143068 | Reference |
1–2 | 49/22574 | 0.80 (0.58–1.09) | 192/22771 | 0.89 (0.76–1.04) | 332/22811 | 0.92 (0.81–1.03) | 2523/22572 | 0.96 (0.92–1.00) |
3–5 | 46/18168 | 1.01 (0.74–1.38) | 137/18121 | 0.83 (0.69–0.99) | 261/18185 | 0.92 (0.81–1.05) | 1868/18122 | 0.90 (0.85–0.95) |
>5 | 27/14049 | 0.68 (0.45–1.03) | 79/13878 | 0.61 (0.48–0.77) | 162/13679 | 0.78 (0.67–0.92) | 1246/13699 | 0.79 (0.75–0.84) |
Continuous | 515/197461 | 0.97 (0.93–1.01) | 1792/197461 | 0.95 (0.92–0.97) | 3098/197461 | 0.98 (0.96–0.99) | 22508/197461 | 0.97 (0.97–0.98) |
No. of endocrine disruptors with any exposure | ||||||||
0 | 428/159266 | Reference | 1508/159413 | Reference | 2604/159562 | Reference | 18768/159666 | Reference |
1 | 42/17198 | 0.95 (0.69–1.32) | 154/17351 | 0.98 (0.83–1.17) | 222/17196 | 0.82 (0.71–0.95) | 1798/17083 | 0.92 (0.87–0.96) |
2 | 25/9561 | 1.02 (0.68–1.55) | 68/9470 | 0.78 (0.61–1.01) | 128/9490 | 0.86 (0.72–1.04) | 974/9532 | 0.88 (0.82–0.95) |
>2 | 20/11436 | 0.61 (0.37–0.99) | 62/11227 | 0.61 (0.47–0.79) | 144/11213 | 0.86 (0.72–1.02) | 968/11180 | 0.76 (0.71–0.81) |
Continuous | 515/197461 | 0.93 (0.84–1.02) | 1792/197461 | 0.90 (0.85–0.95) | 3098/197461 | 0.95 (0.92–0.99) | 22508/197461 | 0.94 (0.92–0.95) |
No. of Prop. 65 reproductive toxicants with any exposure | ||||||||
0 | 485/180295 | Reference | 1705/179906 | Reference | 2864/180147 | Reference | 20857/180276 | Reference |
1 | 23/13352 | 0.64 (0.41–1.00) | 67/13588 | 0.56 (0.44–0.71) | 167/13513 | 0.80 (0.68–0.94) | 1316/13311 | 0.87 (0.82–0.92) |
>1 | 7/3814 | 0.76 (0.36–1.60) | 20/3967 | 0.58 (0.38–0.91) | 67/3801 | 1.18 (0.92–1.52) | 335/3874 | 0.76 (0.68–0.86) |
Continuous | 515/197461 | 0.77 (0.58–1.02) | 1792/197461 | 0.69 (0.58–0.81) | 3098/197461 | 0.97 (0.88–1.07) | 22508/197461 | 0.88 (0.85–0.92) |
No. of reproductive or developmental toxicants with any exposure | ||||||||
0 | 397/144777 | Reference | 1403/144662 | Reference | 2371/144756 | Reference | 17083/145090 | Reference |
1–2 | 54/24235 | 0.85 (0.63–1.14) | 204/24504 | 0.89 (0.77–1.04) | 346/24455 | 0.89 (0.79–1.00) | 2586/24139 | 0.93 (0.89–0.97) |
3–4 | 41/13611 | 1.18 (0.85–1.63) | 102/13451 | 0.83 (0.67–1.02) | 194/13420 | 0.93 (0.80–1.08) | 1432/13459 | 0.92 (0.87–0.98) |
>4 | 23/14838 | 0.57 (0.36–0.88) | 83/14844 | 0.61 (0.48–0.76) | 187/14830 | 0.83 (0.71–0.97) | 1407/14773 | 0.83 (0.78–0.88) |
Continuous | 515/197461 | 0.95 (0.91–1.00) | 1792/197461 | 0.94 (0.92–0.97) | 3098/197461 | 0.98 (0.96–1.00) | 22508/197461 | 0.98 (0.97–0.99) |
Odds ratio adjusted for maternal age (years), race/ethnicity (non-Hispanic white, U.S.-born Hispanic, foreign-born Hispanic, other), education (less than high school, high school, more than high school), parity (1 or ≥2), prenatal care initiated by fifth month (yes vs no), payer source for care (Medi-Cal, private, or other).
This categorization reflects the total number of chemical groups (total possible=67) that an individual was co