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. 2017 Sep 23;8(57):97079–97089. doi: 10.18632/oncotarget.21226

Figure 4. Representative case of osteonecrosis of the femoral head (ONFH) evaluated by magnetic resonance imaging (MRI).

Figure 4

(A) 54-year-old male patient, alcoholic (250 ml of alcohol per day). 1 - 3: There were abnormal signals on the right side of osteochondritis of the femoral head and an extensive area of abnormal signals under the perichondrium. 4 - 6: After treatment with the bone-strengthening pill (BSP) for 6 months, the abnormal signals disappeared and the patient resumed normal work. 7 - 9: The MRI image had no abnormalities at 1-year follow-up. (B) 49-year-old female patient, steroid administration 5 years ago and ONFH for 2 years. 1 - 3: MRI showed slight collapse of the bilateral femoral head. There were large and irregular long T1 and long T2 signals on the anterior superior segment of the bilateral femoral head. STIR revealed that the necrotic lesions exhibited a ladder-like, high, mixed, uneven abnormal signal, disappearance of cartilage signal especially on the left side. 4 - 6: The abnormal signals decreased and the patient could undertake light work after treatment for 6 months. 7 - 9: At 1-year follow up after treatment, the MRI was normal and patient could work as usual.