Table 2. Association of TRG with clinicopathologic factors in 356 patients.
| Characteristic | TRG 1-3 | TRG 4-5 | P |
|---|---|---|---|
| No. (%) | No. (%) | ||
| Age (years) | 0.002 | ||
| ≤60 | 90 (25.3) | 116 (32.6) | |
| >60 | 91 (25.6) | 59 (16.6) | |
| Sex | 0.306 | ||
| Male | 109 (30.6) | 96 (27.0) | |
| Female | 72 (20.2) | 79 (22.2) | |
| cT | 0.003 | ||
| cT1-2 | 19 (5.3) | 5 (1.4) | |
| cT3-4 | 154 (43.3) | 167 (46.9) | |
| Unknown | 8 (2.2) | 3 (3.1) | |
| cN | 0.001 | ||
| N0 | 41 (11.5) | 18 (5.1) | |
| N1/2 | 132 (37.1) | 154 (43.3) | |
| Unknown | 8 (2.2) | 3 (0.8) | |
| ypT category | <0.001 | ||
| T0 | 17 (4.8) | 2 (0.6) | |
| T1 | 17 (4.8) | 3 (0.8) | |
| T2 | 71 (19.9) | 26 (7.3) | |
| T3 | 75 (21.1) | 140 (39.3) | |
| T4 | 1 (0.3) | 4 (1.1) | |
| ypN category | <0.001 | ||
| N0 | 180 (50.6) | 17 (4.8) | |
| N+ | 1 (0.3) | 158 (44.4) | |
| AJCC TNM stage | <0.001 | ||
| pCR | 17 (4.8) | 0 (0) | |
| I | 88 (24.7) | 4 (1.1) | |
| II | 75 (21.1) | 13 (3.7) | |
| III | 1 (0.3) | 158 (44.7) | |
| Pathologic grade | <0.001 | ||
| High | 3 (0.8) | 1 (0.3) | |
| Moderate | 132 (37.1) | 108 (30.3) | |
| Low | 28 (7.9) | 63 (17.7) | |
| Others | 18(5.1) | 3(0.8) | |
| Time interval to surgery | 0.0651 | ||
| ≤Median (18day) | 121 (34) | 113 (31.7) | |
| >Median | 60 (16.9) | 62 (35.4) | |
| Lymphatic invasion | <0.001 | ||
| L0 | 170 (47.8) | 142 (39.9) | |
| L1 | 11 (3.1) | 33 (9.3) |
TRG tumor regression grade.