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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Anesthesiology. 2018 Jan;128(1):117–129. doi: 10.1097/ALN.0000000000001926

Figure 1.

Figure 1

Isoflurane preconditioning improved the recovery of cardiac fnction during post-ischemic reperfusion in Langendorff-perfused C57BL/6 mouse hearts but not db/db mouse hearts. A: left ventricular end-diastolic pressure (mean ± SD); B: left ventricular developed pressure; C: the maximum rate of developed pressure rise (+dp/dt); D: the maximum rate of developed presure decreases (−dP/dt). Control, C57BL/6 mouse hearts undergoing ischemia/reperfusion injury: db/db, db/db mouse hearts undergoing ischemia/reperfusion injury; isoflurane, C57BL/6 mouse hearts treated with 1.4% isoflurane before ischemia; db/db+isoflurane, db/db mouse hearts treated with 1.4% isoflurane before ischemia. *P<0.05 versus control groups, †P<0.05 versus db/db groups, #P<0.05 versus isoflurane groups (n=8 mice/group).