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. 2017 Nov 10;8(61):104492–104507. doi: 10.18632/oncotarget.22355

Table 1. Neurological Severity Scores (NSS).

Evaluation Items Points
Motor tests -
Raising rat by the tail 3
  1 Flexion of forelimb -
  1 Flexion of hindlimb -
  1 Head moved >10° to vertical axis within 30 s
Placing rat on the floor (normal=0; maximum=3) 3
  0 Normal walk -
  1 Inability to walk straight -
  2 Circling toward the paretic side -
  3 Fall down to the paretic side -
Sensory tests 2
  1 Placing test (visual and tactile test) -
  2 Proprioceptive test (deep sensation, pushing the paw against the table edge to stimulate limb muscles)
Beam balance tests (normal=0; maximum=6) 6
  0 Balances with steady posture -
  1 Grasps side of beam -
  2 Hugs the beam and one limb falls down from the beam -
  3 Hugs the beam and two limbs fall down from the beam, or spins on beam (>60 s) -
  4 Attempts to balance on the beam but falls off (>40 s) -
  5 Attempts to balance on the beam but falls off (>20 s) -
  6 Falls off: No attempt to balance or hang on to the beam (<20 s) -
Reflexes absent and abnormal movements 4
  1 Pinna reflex (head shake when touching the auditory meatus) -
  1 Corneal reflex (eye blink when lightly touching the cornea with cotton) -
  1 Startle reflex (motor response to a brief noise from snapping a clipboard paper) -
  1 Seizures, myoclonus, myodystony
Maximum points 18

One point is awarded for the inability to perform the tasks or for the lack of a tested reflex; 13 to 18 indicates severe injury; 7 to 12, moderate injury; 1 to 6, mild injury.