Table 1.
Comparison of symptoms severity scores before and after botulinum toxin A injections
| Before injections, mean (SD) | After injections, mean (SD) | Mean Δ (SD) | 95% CI | p-value | |
|---|---|---|---|---|---|
| Migraine n=90* | 9.34 (0.91) | 5.90 (2.48) | −3.43 (2.46) | [−3.95, −2.92] | <0.001 |
| Photophobia n=90* | 7.91 (2.05) | 5.27 (2.73) | −2.64 (2.56) | [−3.18, −2.11] | <0.001 |
| Dry eye symptoms n=81* | 5.40 (3.41) | 4.68 (3.34) | −0.716 (2.11) | [−1.18, −0.249] | 0.003 |
| No self-reported or documented diagnosis of dry eye | |||||
| Migraine n=63 | 9.17 (0.959) | 5.89 (2.65) | −3.29 (2.63) | [−3.95, −2.62] | <0.001 |
| Photophobia n=63 | 7.68 (1.93) | 5.10 (2.60) | −2.59 (2.53) | [−3.23, −1.95] | <0.001 |
| Dry eye n=57 | 4.40 (3.33) | 3.74 (3.20) | −0.667 (2.29) | [−1.27, −0.060] | 0.032 |
| Self-reported or documented diagnosis of dry eye | |||||
| Migraine n=27 | 9.70 (0.669) | 5.93 (2.07) | −3.78 (2.03) | [−4.58, −2.98] | <0.001 |
| Photophobia n=27 | 8.44 (2.24) | 5.67 (3.03) | −2.78 (2.68) | [−3.84, −1.72] | <0.001 |
| Dry eye symptoms n=24 | 7.75 (2.29) | 6.92 (2.55) | −0.833 (1.66) | [−1.53, −0.133] | 0.022 |
*
90 individuals responded to the pre/post injection migraine and photophobia severity questions while only 81 individuals responded to the pre/post injection dry eye symptoms severity questions.
SD = standard deviation