Figure 1. Expression levels of miR-223 in T-LBL patients.
(A) Boxplot of differential miR-223 expression in T-LBL tumour biopsies (n=67) and in normal thymus tissue (n=5) detected by qRT-PCR (**P=0.003). Data have been calculated according to the comparative delta Ct method (2-ΔΔCt), using RNU6 as endogenous control. The horizontal line in the box indicates the median expression level of miR-223. (B) Heterogeneous expression levels of miR-223 in 67 T-LBL cases. Data have been measured by qRT-PCR according to the comparative delta Ct method (2-ΔΔCt), and compared to normal thymus tissue. Blue and red bars are T-LBL tumor biopsies with higher (> median value) and lower (≤ median value) level of miR-223, respectively. MiR-223 median expression level=18. (C) PFS according to miR-223 expression level. MiR-223 high (>median value), miR-223 low (≤median value).