Table 13. ALDH3B2 haplotype frequencies (%) in cases and controls and risk of ESCC.
Haplotypes | Case (freq) | Control (freq) | Crude OR(95% CI) | p |
---|---|---|---|---|
ALDH3B2Ars34589365Grs3741172Trs4646823Grs78402723Crs7947978Grs866907Grs9787887 | 247 (12.1) | 323 (12.4) | 1.007 [0.840∼1.206] | 0.943 |
ALDH3B2Grs34589365Ars3741172Grs4646823Ars78402723Ars7947978Ars866907Grs9787887 | 184 (9.0) | 219 (8.4) | 1.106 [0.898∼1.363] | 0.344 |
ALDH3B2Grs34589365Grs3741172Trs4646823Grs78402723Crs7947978Grs866907Ars9787887 | 1318 (64.6) | 1735 (66.3) | 1.000 | 1.000 |
ALDH3B2Grs34589365Grs3741172Trs4646823Grs78402723Crs7947978Grs866907Grs9787887 | 235 (11.5) | 279 (10.6) | 1.109 [0.919∼1.338] | 0.281 |
Haplotypes were composited by ALDH3B2 rs34589365, rs3741172, rs4646823, rs78402723, rs7947978, rs866907, rs9787887. All those frequency < 3% were ignored in analysis, most common haplotype ALDH3B2Grs34589365Grs3741172 Trs4646823Grs78402723Crs7947978Grs866907Ars9787887 was selected as reference.