Table 3. Candidate PAX8 co-regulators.
| Motif/Factor | HeyA8 | IGROV1 | ||||||
|---|---|---|---|---|---|---|---|---|
| All | Super enhancer | Promoter | Enhancer | All | Super enhancer | Promoter | Enhancer | |
| PAX5 | -75.64 | -122.14 | -75.64 | -237.09 | -84.48 | -156.36 | -84.48 | -276.91 |
| PAX2 | -76.06 | -140.02 | -76.06 | -242.56 | -90.26 | -202.7 | -90.26 | -253.45 |
| PAX1 | -42.29 | -85.93 | -42.29 | -121.7 | -38.96 | -114.76 | -38.96 | -138.49 |
| PAX6 | -38.46 | -121.77 | -38.46 | -133.79 | -16.11 | -94.49 | -16.11 | -127.34 |
| PAX9 | -35.48 | -58.45 | -35.48 | -83.5 | -26.75 | -76.52 | -26.75 | -95.52 |
| TEAD3 | 0 | 0 | 0 | 0 | 0 | -14.77 | 0 | -25.26 |
| Arnt::Ahr | 0 | -12.34 | 0 | -16.12 | 0 | -13.64 | 0 | -23.05 |
| TEAD1 | 0 | 0 | 0 | 0 | 0 | -22.46 | 0 | -11.55 |
| Zbtb3_primary | 0 | 0 | 0 | -7.92 | 0 | 0 | 0 | -14.5 |
| GMEB2 | 0 | 0 | 0 | -6.17 | 0 | 0 | 0 | -14.07 |
| Klf4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -11.27 |
| Zfp161_secondary | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -9.9 |
| JUND | 0 | -5.81 | 0 | -5.13 | 0 | -8.61 | 0 | 0 |
| SP1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -8.61 |
| Sp4_secondary | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -8.25 |
| FOS | 0 | -5.52 | 0 | -5.23 | 0 | 0 | 0 | -8.21 |
| JUNB | 0 | -5.02 | 0 | -5.18 | 0 | -8.2 | 0 | 0 |
| HIF1A::ARNT | 0 | 0 | 0 | 0 | 0 | -7.76 | 0 | -6.05 |
| Klf1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -7.47 |
| KLF5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -6.28 |
| Nfe2l2 | 0 | 0 | 0 | -6.2 | 0 | 0 | 0 | 0 |
| Max_secondary | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -5.71 |
| NFIA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -5.43 |
| Klf7_primary | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -5.19 |
| KLF14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -5.12 |
| NFYA | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -5.07 |
Log adjusted p-values of motifs found within 50 bases of PAX8 binding site summits of HeyA8 and IGROV1 using all, superenhancer, promoter and enhancer-associated PAX8 binding sites.