Table 5. Genes commonly changing in HeyA8 and IGROV1 models following PAX8 knockdown.
HeyA8 | IGROV1 | ||||
---|---|---|---|---|---|
Gene Name | Fold Change | P-value | Fold Change | P-value | |
AJAP1 | -1.9 | 3.82E-10 | -1.8 | 2.17E-09 | |
ANKRD1 | 1.6 | 2.02E-03 | 10.8 | 4.06E-09 | |
C20orf75 | -1.7 | 9.06E-05 | -2.8 | 8.22E-05 | |
HIST1H2BK | 1.9 | 2.20E-05 | 1.8 | 1.33E-05 | |
HIST2H2AA3 | 2.0 | 8.41E-07 | 1.7 | 2.24E-06 | |
HIST2H2AA4 | 1.9 | 1.79E-06 | 1.6 | 8.88E-07 | |
HIST2H2AC | 1.6 | 1.35E-06 | 1.5 | 3.62E-04 | |
PAX8 | -1.9 | 4.57E-06 | -2.3 | 6.51E-08 | |
PRSS23 | 1.5 | 2.10E-04 | 3.9 | 6.86E-10 | |
SAT1 | 1.8 | 4.47E-07 | 1.7 | 2.75E-05 | |
SIRPA | -1.7 | 2.56E-05 | -1.7 | 1.48E-07 | |
STC1 | 2.7 | 2.51E-05 | 1.8 | 2.18E-05 | |
TGFBR2 | 1.8 | 1.46E-05 | 1.5 | 2.41E-05 | |
VASN | 1.7 | 4.02E-07 | 6.0 | 5.38E-11 |