Table 2. Cox regression analysis of risk factors for cancer-related death in lung cancer patients.
| Characteristics | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P-valuea | HR (95% CI) | P-valuea | |
|
Rab37/TIMP1/PKCα expression |
||||
| +/+/− | 1.00 | 1.00 | ||
| Others | 1.27 (0.68–2.38) | 0.450 | 1.53 (0.78–3.01) | 0.215 |
| +/−/+ | 3.15 (1.55–6.38) | 0.001 | 3.81 (1.66–8.72) | 0.002 |
| Type | ||||
| ADC | 1.00 | --b | ||
| SCC | 1.24 (0.35–1.41) | 0.283 | --b | --b |
| Stage | ||||
| Stage I-II | 1.00 | 1.00 | ||
| Stage III-IV | 1.73 (1.05–2.87) | 0.032 | 1.28 (0.64–2.57) | 0.488 |
| T stage | ||||
| Stage 1–2 | 1.00 | 1.00 | ||
| Stage 3–4 | 1.89 (1.08–3.31) | 0.026 | 1.07 (0.54–2.11) | 0.848 |
| N stage | ||||
| N0 | 1.00 | 1.00 | ||
| > N1 | 1.83 (1.09–3.07) | 0.022 | 1.75 (0.87–3.49) | 0.115 |
| M stage | ||||
| M0 | 1.00 | 1.00 | ||
| > wM1 | 1.83 (1.02–3.29) | 0.042 | 1.01 (0.52–1.95) | 0.987 |
NOTE: ADC, adenocarcinoma; SCC, squamous cell carcinoma; CI, confidence interval; HR, hazard ratio.
aBold values represented statistical significance (P < 0.05).
bThe variables without significant HR in univariate analysis were not included in the multivariate analysis.