Food intake, blood glucose, and corticosterone levels in Th-Cre+ rats after CNO injection. Responses during the 4-hour period after control (0.9% saline intraperitoneally), CNO (1 mg/kg intraperitoneally), or 2DG (250 mg/kg subcutaneously) injection in male Th-Cre+ rats given bilateral AAV-hM3D injections into A1, A1/C1, C1m, or C1r, respectively. (Upper) Food intake; (middle) blood glucose levels in the absence of food; and (lower) plasma levels of corticosterone. #P < 0.05; ##P < 0.01; *P < 0.001 vs saline control at the same time points by post hoc Student-Newman-Keuls test after two-way repeated-measures analysis of variance (six to eight rats for each treatment).