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The Scientific World Journal logoLink to The Scientific World Journal
. 2010 May 18;10:901–916. doi: 10.1100/tsw.2010.81

Stem Cell-Based Dental Tissue Engineering

Petar Zivkovic 1, Vladimir Petrovic 1, Stevo Najman 1, Vladisav Stefanovic 1,*
PMCID: PMC5763752  PMID: 20495769

Abstract

The development of biological and biomaterial sciences profiled tissue engineering as a new and powerful tool for biological replacement of organs. The combination of stem cells and suitable scaffolds is widely used in experiments today, in order to achieve partial or whole organ regeneration. This review focuses on the use of tissue engineering strategies in tooth regeneration, using stem cells and stem cells/scaffold constructs. Although whole tooth regeneration is still not possible, there are promising results. However, to achieve this goal, it is important to understand and further explore the mechanisms underlying tooth development. Only then will we be able to mimic the natural processes with the use of stem cells and tissue engineering techniques.

Keywords: tooth development, stem cells, tooth engineering, dentin-pulp complex, periodontium


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