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. Author manuscript; available in PMC: 2018 Jul 10.
Published in final edited form as: Nature. 2018 Jan 10;553(7688):347–350. doi: 10.1038/nature25187

Extended Data Figure 5. CD8 density and PD-L1 expression in the tumour parenchyma and invasive margins in biopsies of patients with desmoplastic and non-desmoplastic melanoma.

Extended Data Figure 5

A) CD8 staining in the invasive margin. B) PD-L1 staining in the invasive margin. C) CD8 staining in the tumour centre. D) PD-L1 staining in the tumour centre. Percentage of positively stained cells in all nucleated cells are presented. CB: clinical benefit; PD: progressive disease; SD: stable disease; CR: complete response; PR: partial response. All calculations used two-sided Mann-Whitney rank sum test. See supplementary table for all statistical analyses. * Indicates statistical significance.