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. 2017 Nov 6;8(70):114845–114855. doi: 10.18632/oncotarget.22296

Figure 3. Prognostic usefulness of five genes that associated with progression from locally advanced or advanced prostate cancer (PC) to castration-resistant PC (CRPC).

Figure 3

The prognostic cohort consisted of 94 patients with locally advanced or advanced PC (AdvPC) who underwent surgery followed by androgen-deprivation therapy (ADT) and were followed up on average for 32.7 months. The patients were divided into two groups depending on whether they had higher or lower AR, SPINK1, SP8, CEACAM20, or CEACAM22P expression. The time to CRPC in the two subgroups for each gene was analyzed. Higher SPINK1 and lower SP8 expression associated with progression to CRPC.