Figure 2. Early life maternal separation stress resulted in increased anxiolytic behavior in male rats.

Ordinate depicts number of entries and into the open arm relative to total entries in open and enclosed arms of the elevated plus maze ( A and B, respectively) and latency to emerge from the home cage into a novel environment ( C). Line graphs depict mean and standard error of the mean for unstressed (black) and stressed (gray) male rats. *, p < 0.05; **, p < 0.01; unpaired two-tailed Student’s t-test (n = 8 animals in each experimental group).