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. 2017 Dec 19;9(1):1187–1199. doi: 10.18632/oncotarget.23455

Figure 8. GRM1+ exosomes induce invasion in GRM1- cells.

Figure 8

C81-61 cells were incubated with conditioned media from C81-61 or C81-61 GRM1-6 cells and cell proliferation was measured using the MTT cell proliferation assay. Cell proliferation was unaffected by conditioned media from the 2 cell lines on Day 1, 3 and 5 of incubation (A). Migration of C81-61 cells incubated with exosomes released from C81-61 cells (GRM1- exosomes), C81-61 GRM1-6 cells (GRM1+ exosomes) or no exosomes. Results of the representative experiment shows the number of cells in 10 random fields. The number of cells invaded when incubated with exosomes from C81-61 GRM1-6 is significantly higher than those incubated with exosomes from C81-61 cells (p=0.016) (B).